Shawn MacLellan

Associate Professor



Bailey Hall 221


Academic interests

  • Bacteriology
  • Molecular Genetics and Biochemistry
  • Regulation of Gene Expression in Bacteria

Brief biography

Dr. Shawn MacLellan received his BSc and MSc from the Department of Microbiology at the University of Guelph and his PhD from the Department of Biology at McMaster University. He conducted postdoctoral work in the Department of Microbiology at Cornell University in Ithaca, New York.

Courses taught

  • BIOL2023 Introductory Biochemistry
  • BIOL3073 Biochemistry of Gene Expression
  • BIOL4043 Cellular Metabolism

Selected research

Davis MC, Kesthely CA, Franklin EA, MacLellan SR. 2017. The essential activities of the bacterial sigma factor. Can J Microbiol. 63:89-99.

Xue X, Davis MC, Steeves T, Bishop A, Breen J, MacEacheron A, Kesthely CA, Hsu F, MacLellan SR. 2016. Characterization of a protein-protein interaction within the SigO-RsoA two-subunit σ factor: the σ70 region 2.3-like segment of RsoA mediates interaction with SigO. Microbiology. 162:1857-1869.

Davis MC, Smith LK, MacLellan SR. 2016. The atypical two-subunit σ factor from Bacillus subtilis is regulated by an integral membrane protein and acid stress. Microbiology. 162:398-407.

Gaballa A, MacLellan S, Helmann JD. 2012. Transcription activation by the siderophore sensor Btr is mediated by ligand-dependent stimulation of promoter clearance. Nucleic Acids Res. 40:3585-95.

MacLellan SR, Guariglia-Oropeza V, Gaballa A, Helmann JD. 2009. A two-subunit bacterial sigma-factor activates transcription in Bacillus subtilis. Proc Natl Acad Sci USA. 106:21323-8.