This seminar reviews the organization of the human brain and how the brain produces behavior (e.g., thoughts, feelings, movements, perceptions, memories) using evidence from experimental and clinical human neuropsychology. A core set of topics will be used to examine the major neocortical and subcortical regions in the brain together with their associated neuropsychological functions as well as how these regions work together to produce complex adaptive behavior. Additional topics may include experimental and clinical measures of brain functioning and cognitive maturation and decline across the lifespan. Critical thinking about brain-behaviour relationships will be emphasized.