This graduate level course is offered in conjunction with the undergraduate level course POLS 4727 – The Politics of Global Health. This course considers challenges in contemporary global health governance by examining the global response to a specific disease/health issue, focusing on how the global South is implicated in this governance and disease response. Questions we will explore include: how is health global? What is the relationship between ’the global’ and ‘the local’  in global health governance? How effective are various global health strategies, programs and frameworks, and in what ways do they have uneven effects on different populations and regions? What are the power relations between actors including states, international and multilateral organizations, social movements, and the private sector? What are the structural and political drivers of health inequity? This year, we will study these issues through critical assessment of the global response to  HIV/AIDS.