Publications

Journal Articles

Martel P, B O'Connor, T Kovacs, S Semeniuk, M Hewitt, D MacLatchy, M McMaster, J Parrott, MR van den Heuvel, G and Van Der Kraak. Accepted. Effluent monitoring at a bleached kraft mill:directions for best management practices for eliminating effects on fish reproduction. J. Enviorn. Sci. Heal. A.

Gielen GJHP, PW Clinton, MR van den Heuvel, M Kimberley, and LG Greenfield. 2011. Influence of sewage and pharmaceuticals on soil microbial community and function. Environ. Toxicol. Chem. 30(5): 1086-1095.

Kovacs T, P Martel, B O'Connor, J Parrott, M McMaster, G van Der Kraak, D MacLatchy, M van den Heuvel, and LM Hewitt. 2011. Kraft mill effluent survey: progress toward best management practices for reducing effects on fish reproduction. Environ. Toxicol. Chem. 30(6): 1421-1429.

Finley MA, SC Courtenay, KL Teather, MR and van den Heuvel. 2010. Assessment of northern mummichog (Fundulus heteroclitus macrolepidotus) as an estuarine pollution monitoring species. Water Qual. Res. J. Can. 44: 323-332.

Hogan NS, KS Lee, B Köllner, and MR van den Heuvel. 2010. The effects of the alkyl polycyclic aromatic hydrocarbon retene on rainbow trout (Oncorhynchus mykiss) specific immune response. Aquat. Toxicol. 100(3): 246-254.

Landman MJ, NA Bleackley, N Ling, and MR van den Heuvel. 2010. Physiological health of common bully (Gobiomorphus cotidianus) in the Tarawera and Rangitaiki Rivers of New Zealand: evidence of diminished ecological effects of pulp and paper effluents in wild fish populations. Water Qual. Res. J. Can. 45: 223-233.

Parrott JL, ME McMaster, LM Hewitt, T Kovacs, D MacLatchy, P Martel, B O'Connor, G Van Der Kraak, and MR van den Heuvel. 2010. Comparison of field studies with fathead minnow full life cycle tests for the assessment of reproductive effects in pulp and paper effluent. Water Qual. Res. J. Can. 45: 187-200.

van den Heuvel MR, LM Hewitt, T Kovacs, D MacLatchy, G Van Der Kraak, JL Parrott, ME McMaster, P Martel, and B O'Connor. 2010. Comparison of short-term fish reproductive bioassays for predicting reproductive effects in a bleached kraft mill effluent. Water. Qual. Res. J. Can. 45: 175-186.

Fraser DS, K O'Halloran, and MR van den Heuvel. 2009. Toxicity of pulp and paper solid organic waste constituents to soil organisms. Chemosphere. 74(5): 660-668. 

Gielen GJHP, MR van den Heuvel, PW Clinton, and LG Greenfield. 2009. Factors impacting on pharmaceutical leaching following sewage application to land. Chemosphere. 74:537-542.

Wartman CA, NS Hogan, LM Hewitt, ME McMaster, MJ Landman, S Taylor, TG Kovacs, and MR van den Heuvel. 2009. Androgenic effects of a Canadian bleached kraft pulp and paper effluent as assessed using threespine stickleback (Gasterosteus aculeatus). Aquat. Toxicol. 92: 131-139.

Landman MJ, S Taylor, and MR van den Heuvel. 2008. Carotenoid depletion and ovarian dysfunction in common bully exposed to a New Zealand pulp mill effluent. Aquatic. Toxicol. 87(4): 303-309.

Hewitt M, T Kovacs, M Dube, D MacLatchy, P Martel, M McMaster, M Paice, J Parrott, MR van den Heuvel, and G Van Der Kraak. 2008. Altered reproduction in fish exposed to pulp and paper mill effluents: A review of the roles of individual compounds and mill operating conditions. Environ. Toxicol. Chem. 27: 682.

Hogan NS, C Wartman, MA Finley, J van der Lee, and MR van den Heuvel. 2008. Simultaneous determination of androgenic and estrogenic endpoints in the threespine stickleback (Gasterosteus aculeatus) using quantitative RT-PCR. Aquat. Toxicol. 90: 269-276.

Michel C, BJ Hicks, KN Stolting, AC Clarke, MI Stevens, R Tana, A Meyer, and MR van den Heuvel. 2008. Distinct migratory and non-migratory ecotypes of an endemic New Zealand eleotrid (Gobiomorphus cotidianus) -- implications for incipient speciation in island freshwater fish species. BMC Evol. Biol. 8:49.

van den Heuvel, MR, MJ Landman, MA Finley, and DW West. 2008. Altered physiology of rainbow trout in response to modified energy intake combined with pulp and paper effluent exposure. Ecotox. Environ. Safety. 69: 187-198.

Peters LA, M MacKinnon, T Van Meer, MR van den Heuvel, and DG Dixon. 2007. Effects of oil sands process-affected waters and naphthenic acids on yellow perch (Perca flavescens) and Japanese Medaka (Orizias latipes) embryonic development. Chemosphere. 67: 2177-2183.

van den Heuvel MR, C Michel, MI Stevens, AC Clarke, KN Stölting, BJ Hicks, and LA Tremblay. 2007. Monitoring the effects of pulp and paper effluent is restricted in genetically distinct populations of common bully (Gobiomorphus cotidianus). Environ. Sci. Technol. 41: 2602-2608.

Bandelj E, MR van den Heuvel, FDL Leusch, N Shannon, S Taylor, and LH McCarthy. 2006. Determination of the androgenic potency of whole effluents using mosquitofish and trout bioassays. Aquat. Toxicol. 80: 237-248.

Hoeger B, S Taylor, B Hitzfeld, DR Dietrich, and MR van den Heuvel. 2006. Stimulation of reproductive growth in rainbow trout (Oncorhynchus mykiss) following exposure to treated sewage effluent. Environ. Toxicol. Chem. 25: 2753-2759.

Leusch FDL, AME Eriksson, MR van den Heuvel, HF Chapman, SR Gooneratne, and LA Tremblay. 2006. Development of methods for extraction and in vitro quantification of estrogenic and androgenic activity of wastewater samples. Comp. Biochem. Physiol. C. 143: 117-126.

Landman MJ, MR van den Heuvel, M Finley, HJ Bannon, and N Ling. 2006. Combined effects of pulp and paper effluent and hypoxia on swimming performance, metabolism and hematology of rainbow trout. Ecotoxicol. Environ. Safety. 65: 314-322.

Leusch FDL, HF Chapman, MR van den Heuvel, BLL Tan, SR Gooreratne, and LA Tremblay. 2006. Bioassay-derived androgenic and estrogenic activity in municipal sewage in Australia and New Zealand. Ecotoxicol. Environ. Safety. 65: 403-411.

van den Heuvel MR, MJ Landman, and LA Tremblay. 2006. Responses of shortfin eel (Anguilla australis) exposed in situ to pulp and paper effluent. J. Toxicol. Environ. Health. 69(19): 1763-1779.

van den Heuvel MR, FDL Leusch, S Taylor, N Shannon, and B McKague. 2006. Assessment of the Reproductive-Endocrine Disrupting Potential of Chlorine Dioxide Oxidation Products of Plant Sterols. Environ. Sci. Technol. 40: 2594-2600.

West D, N Ling, B Hicks, LA Tremblay, N Kim, and MR van den Heuvel. 2006. Cumulative impacts assessment of fish populations in the Waikato River, New Zealand using brown bullhead (Ameiurus nebulosis) populations. Environ. Toxicol. Chem. 25: 1868-1880.

Ellis RJ, MR van den Heuvel, MA Smith, and N Ling. 2005. Effects of maternal versus direct exposure to pulp and paper mill effluent on rainbow trout early-life-stages. J. Toxicol. Environ. Health. 68: 369-387.

Hoeger B, B Hitzfeld, B Köllner, DR Dietrich, and MR van den Heuvel. 2005. Sex and low-level sampling stress modify the impacts of sewage effluent on the rainbow trout (Oncorhynchus mykiss) immune system. Aquat. Toxicol. 73: 79-90.

Landman MJ, MR van den Heuvel, and N Ling. 2005. Relative sensitivities of common freshwater fish and invertebrates to acute hypoxia. NZ J. Mar. Freshw. Res. 39: 1061-1067.

Tozer W, KJ Wilkins, H Wang, M van den Heuvel, T Charleson, WB Silvester. 2005. Using stable nitrogen isotopes to identify losses of nitrogen from catchments with different land-use practices. Isotop. Environ. Health Stud. 41: 13-30.

Tremblay LA, P Fischer, FDL Leusch, MR van den Heuvel, J-C Nicholas, A Pillon, and P Belaguer. 2005. Potential of Sodium Fluoroacetate (1080) and Fluorocitrate to bind to Androgen and Oestrogen receptors. Austral. J. Ecotoxicol. 11: 155-162.

van den Heuvel MR, K O'Halloran, RJ Ellis, N Ling, and ML Harris. 2005. Immune Responses in Rainbow Trout Exposed to a Pulp Mill Effluent. Arch. Environ. Contam. Toxicol. 48: 520-529.

Höger B, B Köllner, G Kotterba, MR van den Heuvel, B Hitzfeld, and DR Dietrich. 2004. Influence of chronic exposure to treated sewage effluent on the distribution of white blood cell populations in rainbow trout (Oncorhynchus mykiss) spleen. Toxicol. Sci. 82: 97-105.                                                                                                   

Höger B, MR van den Heuvel, BC Hitzfeld, and DR Dietrich. 2004. Effects of treated sewage effluent on immune function in rainbow trout (Oncorhynchus mykiss). Aquat. Toxicol. 70: 345-355.

Slade AH, RJ Ellis, MR van den Heuvel, and TR Stuthridge. Nutrient minimisation in the pulp and paper industry: an overview. Wat. Sci. Technol. 50(3): 111-122.

Ellis RJ, MR van den Heuvel, E Bandelj, MA Smith, LH McCarthy, TR Stuthridge, and DR Dietrich. 2003. In vivo and In vitro assessment of the androgenic potential of a pulp and paper mill effluent. Environ. Toxicol. Chem. 22: 1448-1456.

Landman MJ, and MR van den Heuvel. 2003. An improved system for the control of dissolved oxygen in freshwater aquaria. Water. Res. 37: 4337-4342.

van den Heuvel MR, and RJ Ellis. 2002. Timing of exposure to pulp and paper effluent influences the manifestation of reproductive effects in rainbow trout. Environ. Toxicol. Chem. 21: 2338-2347.

van den Heuvel MR, RJ Ellis, LA Tremblay, and TR Stuthridge. 2002. Exposure of reproductively maturing rainbow trout to a New Zealand pulp and paper mill effluent. Ecotoxicol. Environ. Saf. 51: 65-75.

Parrott JL, MR van den Heuvel, LM Hewitt, MR Servos, MA Baker, and KR Munkittrick. 2000. Isolation of MFO inducers from tissues of white suckers caged in bleached kraft mill effluent. Chemosphere. 41: 1083-1089.

van den Heuvel MR, M Power, J Richards, M MacKinnon, and DG Dixon. 2000. Disease and gill lesions in yellow perch (Perca flavescens) exposed to oil sands mining-associated waters. Ecotoxicol. Environ. Saf. 46: 334-341.

Power M, and MR van den Heuvel. 1999. Variability in YOY yellow perch growth and its relationship to temperature. Trans. Amer. Fish. Soc. 128: 687-700.

van den Heuvel MR, M Power, MD MacKinnon, and DG Dixon. 1999. Effects of oil sands related aquatic reclamation on yellow perch (Perca flavescens). II. Chemical and biochemical indicators of exposure to oil sands related waters. Can. J. Fish. Aquat. Sci. 56: 1226-1233.

van den Heuvel MR, M Power, MD MacKinnon, T Van Meer, EP Dobson, and DG Dixon. 1999. Effects of oil sands related aquatic reclamation on yellow perch (Perca flavescens). I. Water quality characteristics and perch physiological and population responses. Can. J. Fish. Aquat. Sci. 56: 1213-1225.

Harris ML, CA Bishop, J Struger, MR van den Heuvel, GJ Van Der Kraak, DG Dixon, B Ripley, and JP Bogart. 1998. The functional integrity of northern leopard frog (Rana pipiens) and green frog (Rana clamitans) populations in orchard wetlands. I. Genetics, physiology and biochemistry of breeding adults and young-of-the-year. Environ. Toxicol. Chem. 17: 1338-1350.

Whyte JJ, MR van den Heuvel, JH Clemons, S Huestis, MR Servos, DG Dixon, and NC Bols. 1998. Mammalian and teleost cell line bioassay and chemically derived 2,3,7,8-Tetrachlorodibenzo-p-dioxin equivalent concentrations in lake trout (Salvelinus namaycush) from Lake Superior and Lake Ontario, North America. Environ. Toxicol. Chem. 17(11): 2214-2226.

Huestis SY, MR Servos, DM Whittle, MR van den Heuvel, and DG Dixon. 1997. Evaluation of temporal and age-related trends of chemically and biologically generated 2,3,7,8-tetrachlorodibenzo-p-dioxin equivalents in Lake Ontario lake trout, 1977 to 1993. Environ. Toxicol. Chem. 16: 154-164.

van den Heuvel MR, MR Servos, KR Munkittrick, NC Bols, and DG Dixon. 1996. Evidence for a reduction of 2,3,7,8-TCDD toxic equivalent concentrations in white sucker (Catostomus commersoni) exposed to bleached kraft pulp mill effluent, following process and treatment improvements. J. Great Lakes Res. 22: 264-279.

Brown DG, RP Lanno, MR van den Heuvel, and DG Dixon. 1995. HPLC determination of plasma thiocyanate concentrations in fish blood:  application to laboratory pharmacokinetic and field-monitoring studies. Ecotox. Environ. Safety. 30: 302-308.

van den Heuvel MR, KR Munkittrick, GJ Van Der Kraak, MR Servos, and DG Dixon. 1995. Hepatic 7-ethoxyresorufin-O-deethylase activity, plasma steroid hormone concentrations and liver bioassay-derived 2,3,7,8-TCDD toxic equivalent concentrations in wild white sucker (Catostomus commersoni) caged in bleached kraft pulp mill effluent. Can. J. Fish. Aquat. Sci. 52: 1339-1350.

van den Heuvel MR, KR Munkittrick, JJ Stegeman, and DG Dixon. 1995. Second-round interlaboratory comparison of hepatic ethoxyresorufin-O-deethylase activity in white sucker (Catostomus commersoni) exposed to bleached kraft pulp mill effluent. Environ. Toxicol. Chem. 14: 1521-1527.

Clemons JH, MR van den Heuvel, JJ Stegeman, DG Dixon, and NC Bols. 1994. Derivation and comparison of toxic equivalent factors for selected congeners of dioxins and furans using fish and mammalian cell lines. Can. J. Fish. Aquat. Sci. 51: 1577-1584.

Munkittrick KR, GJ Van Der Kraak, ME McMaster, CB Portt, MR van den Heuvel, and MR Servos. 1994. Survey of receiving-water environmental impacts associated with discharges from pulp mills. II. Gonad size, liver size, hepatic erod activity and plasma sex steroid levels in white sucker. Environ. Toxicol. Chem. 13: 1089-1101.

Smith IR, B Marchant, MR van den Heuvel, JH Clemons, and J Frimeth. 1994. Embryonic mortality, bioassay derived 2,3,7,8-tetrachlorodibenzo-p-dioxin equivalents, and organochlorine contaminants in Pacific Salmon from Lake Ontario. J. Great Lakes Res. 20: 479-509.

van den Heuvel MR, KR Munkittrick, GJ Van Der Kraak, MW McMaster, CB Portt, MR Servos, and DG Dixon. 1994. Survey of receiving-water environmental impacts associated with discharges from pulp mills. IV. Bioassay-derived 2,3,7,8-tetrachlorodibenzo-p-dioxin toxic equivalent concentration in white sucker (Catostomus commersoni) in relation to biochemical indicators of impact. Environ. Toxicol. Chem. 13: 1117-1126.

Munkittrick KR, MR van den Heuvel, DA Metner, WL Lockhart, and JJ Stegeman. 1993. Interlaboratory comparison and optimization of hepatic microsomal ethoxyresorufin-O-deethylase activity in white sucker (Catostomus commersoni) exposed to bleached kraft mill effluent. Environ. Toxicol. Chem. 12: 1273-1282.

van den Heuvel MR, LS McCarty, RP Lanno, BE Hickie, and DG Dixon. 1991. Effect of total body lipid on the toxicity and toxicokinetics of pentachlorophenol in rainbow trout (Oncorhynchus mykiss). Aquat. Toxicol. 20: 235-252.

Book Chapters

Köllner B, B Wasserrab, U Fischer, G Kotterba, and M van den Heuvel. 2005. How can toxic effects of pollution of the aquatic environment on the immunocompetence of fishes be detected? - A discussion on the relevance of the biomarkers philosophy. In Hot Spot Pollutants: Pharmaceuticals in the Environment. Editors: DR Dietrich, SF Webb, and T Petry. Elsevier. pp: 143-164.

Ellis RJ, MR van den Heuvel, TR Stuthridge, N Ling, and DR Dietrich. 2004. Lack of estrogenic and endocrine disrupting effects of juvenile rainbow trout exposed to a NZ pulp and paper effluent. In Pulp & Paper Mill Effluent Environmental Fate & Effects. Editors: DL Borton, TJ Hall, RP Fisher, and JF Thomas. DEStech Publications. Lancaster, PA, USA. pp: 67-77.

Hawkins SA, C Hedley, H Orr, MR van den Heuvel, and PV Hodson. 2004. Hazard identificaton of pulp mill solid waste to aquatic species. In Pulp & Paper Mill Effluent Environmental Fate & Effects. Editors: DL Borton, TJ Hall, RP Fisher, and JF Thomas. DEStech Publications. Lancaster, PA, USA. pp: 429-438.

Landman MJ, MR van den Heuvel, and N Ling. 2004. Pulp and paper-effluent hypoxia interactions in fish. In Pulp & Paper Mill Effluent Environmental Fate & Effects. Editors: DL Borton, TJ Hall, RP Fisher, and JF Thomas. DEStech Publications. Lancaster, PA, USA. pp: 506-516.

van den Heuvel MR. 2004. Overview of fish health studies – Progress since 2000. In Pulp & Paper Mill Effluent Environmental Fate & Effects. Editors: DL Borton, TJ Hall, RP Fisher, and JF Thomas. DEStech Publications. Lancaster, PA, USA. pp: 3-13.

van den Heuvel MR, E Bandelj, R Donald, RJ Ellis, MA Smith, M Finley, LH McCarthy, and TR Stuthridge. 2004. Review of reproductive-endocrine effects of a New Zealand pulp and paper mill effluent. In Pulp & Paper Mill Effluent Environmental Fate & Effects. Editors: DL Borton, TJ Hall, RP Fisher, and JF Thomas. DEStech Publications. Lancaster, PA, USA. pp: 55-66.

Bols NC, J Whyte, JH Clemons, D Tom, M van den Heuvel, and DG Dixon. 1997. Use of liver cell lines to develop TCDD equivalency factors and to derive TCDD equivalent concentrations in environmental samples. In Ecotoxicology: Responses, Biomarkers and Risk Assessment. SOS Publications, Fair Haven, NJ. Ch. 23. pp: 329-350.